DNA Fund CEO Chris Miglino Details Shift from ETH & Tether to a $50M Bet on Decentralized AI

Chris Miglino is the CEO and Co-Founder of DNA Fund, a crypto-focused investment and advisory firm with deep roots in digital assets, having backed early projects like Ethereum and Tether.

In this interview, Miglino details DNA’s evolution from pioneering in-game currencies to building a multi-division business spanning advisory, market making, asset management, and global events. He highlights DNA’s high-conviction investment approach—reviewing around 1,000 deals a year but selecting only a handful—and their innovative DNA Deal Desk, which tokenizes venture investments to offer liquidity and early-stage access for investors.

Miglino shares DNA’s major commitment to decentralized AI, particularly through BitTensor, where they’re deploying $50 million to support AI compute infrastructure and subnets. He predicts a future where decentralized AI democratizes access and innovation, drawing parallels to the shift from centralized to decentralized crypto exchanges. Miglino closes by inviting entrepreneurs to engage with DNA’s global community, emphasizing their passion for supporting new ideas and building the next wave of crypto and AI ventures.